Approaches to Help Manage the Most Common Side Effects
It is NOT unusual to experience side effects when starting Tyvaso. If you do experience side effects, the first thing you should do is talk to your doctor or healthcare professional. They will want to first ensure that you are using the Tyvaso Inhalation System properly. Below are some additional tips that may help you if you experience some of the most common side effects associated with Tyvaso.
The following potential approaches to managing the most common side effects with Tyvaso are based on anecdotal evidence and should not be construed as medical advice. United Therapeutics does not recommend or endorse using healthcare products other than as directed or prescribed.
Talk to your doctor about strategies that may help manage the side effects you experience while on Tyvaso.
If you experience cough or throat irritation:
- Try an over-the-counter cough medicine to help reduce cough
- Use a throat spray to numb your throat
- Try drinking cold or hot water
- Avoid holding your breath once you inhale
- Rinse mouth with water (do not swallow the water)
Your doctor may also recommend lowering your dose (taking fewer breaths) until your cough goes away, so make sure you talk to your doctor.
If you experience nausea or diarrhea:
- Eat a small meal before treatment
- Try taking an over-the-counter antidiarrheal
- Rinse your mouth with water after treatment
If you experience headaches:
Next: Important Information if You’ve Just Been Prescribed Tyvaso
- Use an over-the-counter pain reliever (like acetaminophen)
- Talk to your doctor to see if slowing the pace at which you increase your dose could help
IMPORTANT SAFETY INFORMATION FOR TYVASO
- Tyvaso is breathed in (inhalable) through your mouth into your lungs. Tyvaso should only be used with the Tyvaso Inhalation System.
Before you take Tyvaso, tell your healthcare provider about all of your medical conditions, including if you:
- Have a lung disease (such as asthma or chronic obstructive pulmonary disease (COPD)).
- Have a lung infection.
- Have liver or kidney problems, as your ability to tolerate Tyvaso may be affected.
- Have low blood pressure, as Tyvaso may cause symptomatic hypotension (low blood pressure).
- Are pregnant or plan to become pregnant. It is not known if Tyvaso will harm your unborn baby. Women who can become pregnant should use effective birth control while taking Tyvaso.
- Are breast-feeding or plan to breast-feed. It is not known if Tyvaso passes into your breast milk.
It is important to tell your healthcare provider about all the medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements, as they may affect your use of Tyvaso by increasing the risk of side effects or decreasing effectiveness. Especially tell your healthcare provider if you take any of these medicines:
Medicines that decrease blood clotting such as warfarin or heparin, as Tyvaso reduces the ability of your
blood to clot (coagulate), and increases your risk for bleeding if you are taking blood thinners
Diuretics (water pills), antihypertensives (medications used to treat high blood pressure or heart
disease), or other vasodilators (medications that lower blood pressure), as Tyvaso may increase your
risk for hypotension (low blood pressure).
Gemfibrozil such as Lopid (for high cholesterol) or rifampin such as Rimactane, Rifadin, Rifamate or
Rifater (for infection), as your Tyvaso dosage may need adjustment.
The most common side effects of Tyvaso are coughing, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), and fainting or loss of consciousness. These are not all the possible side effects of Tyvaso. Tell your healthcare provider about any side effects that bother you or do not go away. Your healthcare provider may be able to help you manage the side effects.
Tyvaso is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH) (WHO Group 1), which is high blood pressure in the arteries of your lungs. Tyvaso can improve exercise ability in people who also take bosentan (an endothelin receptor antagonist, (ERA)) or sildenafil (a phosphodiesterase-5 (PDE-5) inhibitor). Your ability to do exercise decreases 4 hours after taking Tyvaso.
The effects of Tyvaso are unknown in patients under 18 years of age.
Please see the Full Prescribing Information, Patient Package Insert, and the Tyvaso Inhalation System Instructions for Use manual.
For additional information about Tyvaso, visit www.tyvaso.com or call 1-877-UNITHER (1-877-864- 8437).
Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.
This information is provided for an informational purpose and is not intended as treatment advice. Patients should consult a healthcare professional for treatment advice.