How Tyvaso Works

Tyvaso is an inhaled prostacyclin analogue used to treat pulmonary arterial hypertension (PAH) (WHO Group 1). People with PAH have too little prostacyclin in their bodies. Tyvaso mimics some of the effects of natural prostacyclin in the body. It opens up pulmonary arteries, allowing blood to flow more easily. Prostacyclin also helps to keep pulmonary arteries open and working properly, so there is less stress on the heart.

How it works

  1. Tyvaso is inhaled directly into the lungs.
  2. It dilates, or opens up, the arteries between the lungs and heart.
  3. It prevents blood platelets from clumping together.
  4. It allows the heart to pump blood more easily into the lungs.

Selected Important Safety Information

Next: Learn About the Tyvaso Inhalation System.


Before you take Tyvaso, tell your healthcare provider about all of your medical conditions, including if you:

It is important to tell your healthcare provider about all the medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements, as they may affect your use of Tyvaso by increasing the risk of side effects or decreasing effectiveness. Especially tell your healthcare provider if you take any of these medicines:

The most common side effects of Tyvaso are coughing, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), and fainting or loss of consciousness. These are not all the possible side effects of Tyvaso. Tell your healthcare provider about any side effects that bother you or do not go away. Your healthcare provider may be able to help you manage the side effects.


Tyvaso is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH) (WHO Group 1), which is high blood pressure in the arteries of your lungs. Tyvaso can improve exercise ability in people who also take bosentan (an endothelin receptor antagonist, (ERA)) or sildenafil (a phosphodiesterase-5 (PDE-5) inhibitor). Your ability to do exercise decreases 4 hours after taking Tyvaso.

The effects of Tyvaso are unknown in patients under 18 years of age.


Please see the Full Prescribing Information, Patient Package Insert, and the Tyvaso Inhalation System Instructions for Use manual.

For additional information about Tyvaso, visit or call 1-877-UNITHER (1-877-864- 8437).

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at or call 1-800-FDA-1088.

This information is provided for an informational purpose and is not intended as treatment advice. Patients should consult a healthcare professional for treatment advice.