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TYVASO and TYVASO DPI are approved for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3) to improve the ability to exercise.

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Specialty Pharmacy

Working with the Specialty Pharmacy

TYVASO is available only through Specialty Pharmacies, which focus on providing you with in-home training and 24-hour support. Your Specialty Pharmacy (SP) provider is part of your healthcare team.

What happens next: Your SP provider will call you. Answer the call: When they first reach out to you, the SP provider will call you from an 866 or 877 number that you may not recognize. Since they cannot get the medicine to you unless they speak to you, be sure to answer the call to get started and to stay on track.

An SP nurse will give you personal instructions on using TYVASO and provide ongoing support. Your SP nurse may visit or call regularly as you are getting comfortable using TYVASO.

Here’s what to expect when starting TYVASO:

Referral

Your doctor will send a referral for your TYVASO prescription to a Specialty Pharmacy (SP) or United Therapeutics Cares™. Your SP provider is part of your healthcare team and focuses on providing you with in-home training and 24-hour support.

Insurance

Your SP provider or United Therapeutics Cares will process your referral and contact your insurance company to determine and verify coverage for you.

Approval

Your SP provider or United Therapeutics Cares Patient Navigator will contact you to review your coverage and benefits, and if you don’t have insurance, they can help you explore other financial options. Once your referral is approved, they will work with you to coordinate delivery of TYVASO.

Delivery and Demonstration

Your SP nurse or United Therapeutics Cares Patient Navigator will contact you to schedule a virtual or in-person appointment at your home to teach you how to use TYVASO. Your TYVASO system and supplies will be delivered a couple of days before your appointment.

Follow-up and Refills

Your SP nurse or United Therapeutics Cares Patient Navigator can arrange follow-up visits to support you as you get used to using TYVASO. Every 4 weeks, you’ll receive a refill shipment of supplies.

Learn more about cost assistance for your TYVASO prescription.

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IMPORTANT SAFETY
INFORMATION

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
EXPAND

IMPORTANT SAFETY
INFORMATION

COLLAPSE

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Are pregnant or plan to become pregnant. It is not known if either product will harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if either product passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Either product and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)

What are the possible side effects of TYVASO or TYVASO DPI?

Both products can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, either product may lower your blood pressure more.
  • Bleeding problems. Either product may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

The most common side effects of both products are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, diarrhea, and shortness of breath. Like other inhaled prostaglandins, you may have trouble breathing after taking TYVASO or TYVASO DPI because it may cause the muscles around your airway to tighten (bronchospasm). These are not all the possible side effects. Call your doctor for medical advice about side effects or if you have trouble breathing.

You may report side effects to the FDA at 

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or call 1-800-FDA-1088.

What are TYVASO and TYVASO DPI?

TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are prescription medicines used in adults to treat:

  • Pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO or TYVASO DPI can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO or TYVASO DPI. It is not known if TYVASO or TYVASO DPI is safe and effective in children under 18 years of age.
  • Pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3), which is high blood pressure in the lungs due to inflammation and sometimes scarring in the lungs. TYVASO or TYVASO DPI can improve the ability to exercise.

The risk information provided here is not comprehensive. To learn more about TYVASO or TYVASO DPI, talk with your healthcare provider. Please see Full Prescribing Information for TYVASO or TYVASO DPI, Instructions for Use manuals for TD-100 and TD-300 TYVASO® Inhalation System and TYVASO DPI® Inhalation Powder, and additional information at www.TYVASO.com or call 1-844-UNITHER (1-844-864-8437).


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TYVASO and TYVASO DPI are registered trademarks of United Therapeutics Corporation.

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