Waking
TYVASO FITS INTO YOUR DAILY ROUTINE
It is important that you take TYVASO 4x daily to get the full benefit of the medicine.
TYVASO NEBULIZER
Fits into your day
This portable nebulizer allows for dosing at home or on the go.
A simple way to remember: count to 4 and add 1 more
Set up device 1x each morning
Each session takes about 2-3 minutes
Take TYVASO 4x daily during waking hours
Clean device 1x each night
Lunch
Dinner
Bedtime
Reaching your target maintenance dose
Your doctor will work with you to increase the number of breaths per session each week until you reach the target maintenance dose of 9-12 breaths, 4x daily. This process is called “titration.”
Typically, people taking TYVASO start with 3 breaths, 4x daily, and increase by 1 breath each week until they reach the target dose of 9-12 breaths.
*Your doctor may recommend a slightly different schedule.
Reaching your target maintenance dose to maximize benefits
It is important to reach your target maintenance dose so that you can get the full benefit of the medicine and be more active.
At week 16 in the clinical study, patients achieving 10-12 breaths with the TYVASO nebulizer had a 67% greater improvement in their 6-minute walk test (6MWT) distance than those only achieving 7-9 breaths.
59 feet is about 18 meters. 98 feet is about 30 meters.
The Titration Process: Tina’s Story
Listen to Tina share her experience titrating with TYVASO in order to reach her target maintenance dose.
See the patient brochure for more information.
Watch How to Use the TYVASO Nebulizer
TYVASO is delivered through a portable nebulizer.
Download the TYVASO Nebulizer Quick Tips Guide for helpful tips on setting up, operating, transporting, and cleaning your device.
Download the full Instructions for Use manual for the complete, detailed instructions on operating your device.
Find out about TYVASO DPI.
DPI=dry powder inhaler.
IMPORTANT SAFETY INFORMATION
Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:
- Have low blood pressure
- Have or have had bleeding problems
IMPORTANT SAFETY INFORMATION
Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:
- Have low blood pressure
- Have or have had bleeding problems
- Have asthma or chronic obstructive pulmonary disease (COPD)
- Are pregnant or plan to become pregnant. It is not known if either product will harm your unborn baby.
- Are breastfeeding or plan to breastfeed. It is not known if either product passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Either product and other medicines may affect each other.
Especially tell your healthcare provider if you take:
- Medicines used to treat high blood pressure or heart disease
- Medicines that decrease blood clotting (anticoagulants)
- Water pills (diuretics)
- Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)
What are the possible side effects of TYVASO or TYVASO DPI?
Both products can cause serious side effects, including:
- Low blood pressure (symptomatic hypotension). If you have low blood pressure, either product may lower your blood pressure more.
- Bleeding problems. Either product may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).
The most common side effects of both products are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, diarrhea, and shortness of breath. Like other inhaled prostaglandins, you may have trouble breathing after taking TYVASO or TYVASO DPI because it may cause the muscles around your airway to tighten (bronchospasm). These are not all the possible side effects. Call your doctor for medical advice about side effects or if you have trouble breathing.
You may report side effects to the FDA at
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or call 1-800-FDA-1088.
What are TYVASO and TYVASO DPI?
TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are prescription medicines used in adults to treat:
- Pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO or TYVASO DPI can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO or TYVASO DPI. It is not known if TYVASO or TYVASO DPI is safe and effective in children under 18 years of age.
- Pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3), which is high blood pressure in the lungs due to inflammation and sometimes scarring in the lungs. TYVASO or TYVASO DPI can improve the ability to exercise.
The risk information provided here is not comprehensive. To learn more about TYVASO or TYVASO DPI, talk with your healthcare provider. Please see Full Prescribing Information for TYVASO or TYVASO DPI, Instructions for Use manuals for TD-100 and TD-300 TYVASO® Inhalation System and TYVASO DPI™ Inhalation Powder, and additional information at www.TYVASO.com or call 1-877-UNITHER (1-877-864-8437).
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